Protein folding is really complex mechanism and great development in its apprehension has been achieved in last 20years due to the development and usage of some sophisticated modern techniques like X Ray Crystallography, N.M.R, and Mass Spectrometry etc. Protein turn uping refers to the procedure by which a protein assumes its characteristic construction, known as the native province. In this assignment, I have tried to depict the mechanism of the protein folding and consequence of assorted factors which influence protein folding by taking into consideration the present developments in our apprehension of thermodynamics and dynamicss of protein. These molecules help in the folding of the certain protein molecules and besides prevent the flowering of the molecules. Sometimes proteins require aid in folding, molecules which help in the folding are known as chaperones. For proper look of protein, the amino acid concatenation should be in its alone 3D construction. Many diseases like Alzheimer ‘s Parkinson, cystic fibrosis etc (Baldwin 2007) is caused due to improper folding of proteins. Assorted forces and factors are responsible for protein turn uping.If right look of the protein will non take topographic point, it will do upsets in human organic structure.

Proteins are the concatenation of amino acids which binds with polypeptide anchor and so turn up in a alone 3D (native) construction by which protein look takes topographic point. They are responsible for look of certain characters in different types of cells and represent about 50 % of the entire cell dried mass. Proteins are the bio molecules which play polar function in this life universe. Review the mechanism of protein folding Faculty: Enzyme Technology and Biocatalysts Module leader: Prof.

Hydrophilic vs hydrophobic amino acids